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发明公开
CN1931138A 恩替卡韦颗粒剂及其制备方法 无效 - 撤回

恩替卡韦颗粒剂及其制备方法
摘要：
本发明涉及一种治疗乙型肝炎的药物——恩替卡韦的颗粒剂及其制备方法。本发明的目的在于弥补现有技术的不足，为广大医疗工作者和乙型肝炎患者提供一种兼具固体制剂的剂量准确、质量稳定、便于生产、方便携带的特点，和口服液体制剂的易于吞服、生物利用度高、对肠胃刺激性小等特点的恩替卡韦颗粒制剂，并提供了该制剂形式的制备方法。本发明以恩替卡韦为原料，加入适量的适用于制备颗粒剂的药用辅料，按照制剂学的常规技术制成。
摘要（英）：

The present invention relates to entecavir granule as one hepatitis B treating medicine and its preparation process, and aims at providing one kind of entecavir granule preparation with the features of accurate dosage, stable quality, easy production and convenient carrying like other common solid preparation, and the features of easy swallow, high bioavailability, less stimulation on gastrointestinal tract, etc like orally taken liquid preparation. The entecavir granule is prepared with entecavir as main material and proper amount of medicine supplementary material and through a conventional technological process.

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