The related data acquisition and control system for radiation imaging comprises: an image checkup subsystem, an accelerator, a module circuit for digital detector, the Ethernet, and a module circuit for data acquisition and control. Wherein, the last module circuit includes a differential circuit, a buffer circuit, a generation circuit for data storage and control time sequence, a data storage circuit, a network SCM, an accelerator CP isolation drive circuit, a process circuit for accelerator beam strength information, and a constant voltage power circuit.