This invention discloses a method and a device for generating orthogonal variable spread spectrum factor codes of WCDMA, in which, said device includes an orthogonal variable spread spectrum factor code tree storage with 16 spread spectrum factors, a channel code number analysis module, a code tree selection module, a multiplier module and an orthogonal variable spread spectrum factor code counter, and the channel code number analysis module is used in analyzing input channel code number into two channel numbers with corresponding spreqd spectrum factors of 16 to read corresponding number from the code tree list storage.