An axial rotational flow sand removal device on a wellhead of an oil well is applied to the crude oil sand removal on an oil production wellhead in an oilfield, which is characterized in that a shrinkage tube and a diffusion tube are perpendicularly welded with the center line of a sand storage tank, the center lines of the shrinkage tube and the diffusion tube are on the same straight line, and a venturi tube is formed inside the shrinkage tube and the diffusion tube after connecting, an axial rotary vane is fixed on the shrinkage section of the venturi tube, a ring-shaped groove is arranged on the middle portion of the straight tube section of the venturi tube, 3-6 tangential sand throwing holes are arranged on the ring-shaped groove, and the rotary direction of the sand throwing holes is consistent with the rotary direction of the rotary vane, and a sand discharge port is arranged on the bottom of the sand storage tank. The axial rotational flow sand removal device has the effects of small volume of the sand removal device, high pressure resistance, low cost, excellent sand removal effect, simple operation and long service life, which can remove sand without stopping, and does not affect well opening time rate and oil well yield.