The utility model provides an upper guide plate adjustment device for a seamless steel-tube punch unit. A worm and gear 1 is arranged in a shell and is fixedly connected with a frame of the punch unit; a screw rod 5 is screwed in a worm wheel; two synchronous telescopic oil cylinders 4 are arranged at the two lower ends of a press plate 2; the middle part is fixed with a sliding framework 3; and the lower end of the screw rod is pressed in the groove in the middle of the upper surface of the press plate. When in use, the position of the lower end surface of the screw rod is adjusted according to the hole pattern, which is realized in a way that a motor drives the worm and gear. The upper guide plate and a lower guide plate are hoisted on a sliding carriage of the lower guide plate and then are pushed in the guide plate installation position; then the sliding device of the upper guide plate is fell until the sliding device is in contact with the guide plate and the automatic clamping of the guide plate is realized; the sliding framework of the upper guide plate is hoisted until the sliding framework is in full contact with a screw-down screw rod; therefore, the adjustment of the upper guide plate and the installation of the upper and the lower guide plates are finished.