The utility model discloses an approximate square plane superlarge space prestressed steel lattice structure roof which has a steel lattice structure and formed by the mutual orthogonal connection offusiform space pipe trusses and four-pieces holder brace rod type cable-stayed self-balancing orthogonal space pipe trusses at the same height positions in the same plane, wherein the ratio L1/L2 between a long side L1 and a short side L2 of the roof plane is less than 1.5 and greater or equal to 1, the length of the side L1 is less than or equal to 165 meters and greater than or equal to 120 meters, and the length of the side L2 is less than or equal to 150 meters and greater than or equal to 90 meters, the center structures heights of the fusiform space pipe trusses and the holder brace rodtype cable-stayed self-balancing orthogonal space pipe trusses are same and in the range of L2/18 to L2/16, each piece of the holder brace rod type cable-stayed self-balancing orthogonal space pipe trusses takes fusiform space pipe truss as a basic frame body which is formed by connecting an upper chord, a lower chord and an inclined web member, and the two ends of the basic frame body are connected with cast steel nodes which are connected with an upper support bar, a lateral brace rod and a lower support bar. The approximate square plane superlarge space prestressed steel lattice structure roof has the advantages of low occupied space height, little steel consumption, reliable structure property, easy manufacturing and construction, low cost and the like.