The utility model relates to a remote control isolation switch of a transmission and distribution power circuit. The remote control isolation switch consists of an isolation switch, a motor, a control box, a control cable and a remote controller; the control box comprises a remote control receiver and a contactor and is arranged under the isolation switch through the control cable; one side of the isolation switch is provided with the motor; the remote controller starts up the contactor of the control box; and the motor drives the isolation switch to realize the on/off operation. The remote control isolation switch has the advantages that: the remote control isolation switch does not need to reach the bottom of a pole, and can realize the on/off operation within 150 meters by remote control, so labor is saved, the working efficiency is greatly improved, and the automation level of equipment operation of a circuit management department is promoted; and more importantly, the successful development of the remote control isolation switch stops misoperation and farthest ensures the safety of operators.