Disclosed is a hydropower station underground powerhouse concrete ledge excavation steel pipe drilling sample frame. The sample frame is provided with a supporting bent, guiding bents and an operating platform, the supporting bent is provided with at least two horizontal supporting layers, at least one vertical supporting layer and at least one inclined supporting layer, wherein one end of each of the two horizontal supporting layers is fixed on a rock stratum, bottom ends of the vertical and inclined supporting layers are fixed on the ground, and each supporting layer is formed by fixing steel pipes which are arranged at the same interval longitudinally. The supporting bent is provided with at least one row of guiding bents, each row of guiding bents is formed by connecting two longitudinal connecting pipes, guiding pipes distributed according to drilling space and fasteners, each guiding pipe is provided with an inner pipe and an outer pipe, a drill pipe is installed in an inner bore of each inner pipe, and the central line of the guiding pipe is consistent with that of a designed blast hole. The operating platform is formed by arranging and fixing horizontal and vertical steel pipes. Except the inner pipes, the steel pipes of the sample frame adopts seamless steel pipe with diameter of 48mm. The sample frame has easy obtained material, simple structure, convenient construction, fine stability, high drilling precision and fine excavation quality, and creates the optimum indexes including rock bench average over-break is 2.9cm, smooth blasting hole radius rate approaches 100% and irregularity degree ranges from 0cm to 4cm, and can be used for drilling constructions for hydropower station underground powerhouse concrete ledge excavation or for similar complicated profiles with high blast shaping requirements.