An industrial high-resolution observation device for X-ray negative films relates to shooting and digitizing devices, and is used for realizing the digital process on the X-ray negative films detecting industrial welding seams. The device includes a light source (1), a zoom lens (3), a digital camera (6) connected with the lens (3), and a computer (10) connected with the digital camera (6), and further includes a snoot (2), a moving mechanism, a focusing mechanism, and a stepper motor controller (9), wherein the computer (10) owns definition-judging and automatic-focusing programs. LED uniform strong light are used to transmit the films and to achieve illumination, the zoom macro lens and the industrial area-array digital camera are used to acquire the images of the films and the acquired images are transmitted to the computer in a real-time manner. An operator can send instructions through the computer, drive and operate the system, scale the acquired images of the films and then observe the local details of the films. During the zooming process, the computer drives the focusing mechanism through the definition-judging and automatic-focusing algorithms to realize the real-time automatic focusing and ensure that images have no distortion during the zooming.