The utility model discloses a whole set drainage device for emergency rescue of mine water trouble, comprising a mixed flow relay pump, a submersible pump, a drainage pipeline formed by sealing connection of drainpipes, and an explosion isolation transformer station matched with the mixed flow relay pump and the submersible pump, the discharge outlet of the mixed flow relay pump and the water suction port dome of the submersible pump are communicated together to form a serial connection relay drainage system, the drainpipe is provided with a fast-assembling joint capable of being sealed; the explosion isolation transformer station and the serial connection relay drainage system are provided with a wheel walking mechanism or are disposed on the bearing vehicle; The whole set drainage device in the utility mode can quickly pass through the bearing vehicle and transport the drainage system, pipeline, and transformer station to the field when the mine water trouble happens, since the device is a whole set device, the device is advantaged by strong generality, improving dismounting and installation efficiency, performing drainage work after fast assembly, capability of being adapted to requirement for rescue time when the mine water trouble happens, winning time for rescue and relief work, and improving efficiency of water trouble treatment.