The utility model relates to a high-resolution day and night dual-use multipoint varifocal lens applicable to a video shooting system, which comprises a main tube, a front lens group A with negative focal power, and a rear lens group B with positive power, and is characterized in that the inner front side and inner rear side of the main tube are respectively provided with a front lens group seat for installing the front lens group A and a rear lens group seat for installing the rear lens group B; an iris diaphragm C is arranged between the front lens group A and the rear lens group B; and along the incident direction of the light, the front lens group A is sequentially provided with a negative selenodont lens A1, a double-concave lens A2 and a positive selenodont lens A3, the rear lens group B is sequentially provided with a double-convex lens B1, a negative selenodont lens B2, and a positive selenodont lens B3 and a negative selenodont lens B4 that are glued together, as well as a double-convex lens B5 and a double-convex lens B6. The lens is wide in applicable spectrum range and beneficial to realization of clear imaging through infrared light compensation under the low luminance at night, realizes confocal wide spectrum, and the imaging resolution can reach up to 1,300,000 pixels.