A special disposable sterilizing napkin for wiping hands for preventing nosocomial infections used by medical personnel belongs to special disinfection articles used by medical personnel. The sterilizing napkin body is cotton non-woven cloth with a layered structure soaked by antiseptic solution comprised of benzalkonlum bromide, trichlorohydrocarbon diphenyl ether, aseptic distilled water and handguard agent. The sterilizing napkin body is provided with a napkin drawing ring integrally, and one or several sterilizing napkins are packed in a plastic bag which possesses a convenient glue seal. The sterilizing napkin possesses a simple structure, the operation is convenient, and the sterilizing napkin is time saving. The medical personnel can use the sterilizing napkin to process hands and appliances in diagnosis and treatment work, which not only achieves the purpose of sterilizing hands, but also satisfies the requirement of Ministry of Health in the . Simultaneously, dirt contaminated on hands can be removed. In addition, a tin of a stethoscope, a percussion hammer, a pen, etc. can be wiped for disinfection after used in diagnosis and treatment, thus hospital infection control requirements of health administrative departments can be satisfied.