The utility model provides a medicine storage box in a refrigerator. The technical scheme of the utility model is as follows: the medicine storage box comprises two side walls, a back wall, a front wall, a first grate, a box bottom, a label box and a second grate, wherein the two side walls, the back wall, the front wall and the box bottom are integrated through injection molding, the inner sides of the back wall and the front wall are provided with slots of the first grate and a slot of the second grate, the first grate is inserted in the slot of the first grate, the second grate is inserted in the slot of the second grate, and the label box is fixed on the outer surface of the front wall. According to the medicine storage box in the refrigerator, disclosed by the utility model, the interior of the medicine storage box is divided into a plurality of medicine storage spaces by the first grate and the second grate, the plurality of medicine storage spaces are used for storing different types of medicines, and labels with medicine names are inserted into the label box, thus a user can see information written on the labels when opening the refrigerator. Different batches of medicines can be arranged from front to back, thus the medicines are arranged orderly and is clear at a glance, and speed and accuracy of taking out medicines are increased.