The utility model discloses a swirling airflow powder sieving device. The swirling airflow powder sieving device comprises a base and a powder sieving chamber, wherein the powder sieving chamber is arranged on the base and is provided with a sealed upper cover; a powder inlet formed in the sealed upper cover is communicated with an external powder inlet channel through a control valve; double arc partition boards are arranged inside the sealed upper cover concentrically; a sample dividing sieve is arranged in the powder sieving chamber horizontally; an air outlet pipeline connected with the air outlet of an air filter is extended into the powder sieving chamber from the bottom to be communicated with an air nozzle below the sample dividing sieve; and the power outlet pipeline formed below the powder sieving chamber is communicated with a negative pressure collection device. The swirling airflow powder sieving device has the advantages that the sample dividing sieve is convenient to replace; ultrafine powder with different particle sizes can be sieved accurately; the maximum particle size of finished fire powder can be controlled accurately; and the overall sieving device is closed negative pressure environment, so that the dust pollution generated by the sieved powder is prevented effectively, simultaneously, the pollution to Chinese medicament fine powder caused by dirt in air is prevented, and when powder is sieved by using the swirling airflow powder sieving device, the uprush of airflow plays a role in cleaning a net and the problem about sample dividing sieve blockage is also avoided.