The utility model discloses a combined type oxygen concentration monitoring experimental device which comprises an experimental box, wherein the experimental box is mainly formed by connecting two or more transparent unit cavities in a stage mode, and two side walls of each unit cavity are respectively provided with an inlet hole and an outlet hole. Among the two adjacent unit cavities, the outlet hole of a former one stage unit cavity is connected with the inlet hole of a latter one stage unit cavity so that the interiors of the two adjacent unit cavities can be communicated with each other. The inlet hole of a first stage unit cavity forms an air inlet hole of the experimental box. The air inlet hole is connected with an air supply pot which is arranged outside the experimental box through an air inlet control valve. The outlet hole of a last stage unit cavity forms an air outlet of the experimental box. The air outlet is communicated with air outside the experimental box. The combined type oxygen concentration monitoring experiment device can be used for observation of reactions of experimental animals inside the experimental device to different oxygen concentrations after the experimental animals are injected with different inference factors, and provides reliable experimental data for follow-up researches of restraining oxygen therapy harm drugs.