The utility model relates to a working environment monitoring and conditioning system for a 10kV power distribution station. According to the system, a central controller is connected with an air conditioner controller for a plurality of air conditioners so as to transmit corresponding control instructions, and is further connected with an isolated relay output card so as to transmit corresponding control instructions to a plurality of draft fans, the closeness can be guaranteed when the air conditioners are switched, the fans can be switched on and the air conditioners can be switched off when the ventilation is required, and thus, the energy saving and emission reduction are realized. The central controller is used for receiving acquired temperature and humidity data through being connected with a plurality of temperature and humidity sensors, and used for displaying a state through being connected with a touch screen. The central controller is further used for receiving alarm signals which are transmitted by a gas leak detection device through a digital input card, and controlling to switch on the draft fans and open a louver so as to guarantee the safety. According to the energy-saving system, the work demands of field staff can also be given consideration, so that the intellectualization of indoor environment monitoring and conditioning is achieved.