Provided is a frame column construction operation frame. A frame body is provided with a protection device, an operation platform and a base, wherein the horizontal section of the frame body reversed-U-shaped. A jacking device is respectively welded at one end of each of two longitudinal beams of the base, and the two jacking devices are in jacking connection with a building structure profile steel girder through a U-shaped carrier body and an I-beam. The reversed-U-shaped opening end of the operation frame is inserted into a frame column by aid of a hoist, the base is arranged on a floor plate, the operation frame is inwards pushed toward the interior of a building and is led to keep a specified distance from the frame column, the I-beam and the profile steel girder are firmly combined in press fit mode through the jacking devices, the operation fame is fixed on the floor plate under counterforce of the profile steel girder, and accordingly any project operation of the frame column can be carried out. The frame column construction operation frame is simple in structure, convenient to mount and demount and random and flexible in installation position, omits work load of embedding ground anchor during installation, is hoisted integrally, enables workers to carry out construction on the operation frame after being fixed, can be recycled and reduces project cost and manpower resource investment.