The utility model discloses a clamp type semi-automatic injection pen. The clamp type semi-automatic injection pen comprises a push rod protection sleeve, a middle body and a needle outer protection sleeve which are connected successively; a push rod hole sleeve is connected in the bottom end of the middle body, a hanging buckle is arranged in the middle body, a button is arranged in a through hole at the bottom end of the push rod hole sleeve and sleeved with the push rod hole sleeve through a positioning groove, and a button spring is arranged between the button and the hanging buckle; a bottle installation clamp body is arranged in an inner cavity of the middle body, a rib is arranged on the outer surface of the bottle installation clamp body, a spring is arranged between the rib and the hanging buckle, at least two barbs are arranged at the bottom end of the bottle installation clamp body, a medication containing clamp type bottle is sleeved in an inner cavity of the bottle installation clamp body, and a movable rubber plug of the medication containing clamp type bottle is contacted with a push rod; and a double-edge injection needle is arranged at a bottle opening end of the medication containing clamp type bottle, a vent needle sleeve is arranged on the periphery of the double-edge injection needle, and a buffer pad is arranged on the inner end surface of a through hole of the needle outer protection sleeve. The clamp type semi-automatic injection pen is high in accuracy and safety of injected doses.