The utility model provides a brake lever locating mechanism of a fishing line wheel. The brake lever locating mechanism comprises a brake lever, a lever handle, two clamping pins, a release hole and a release button. Two clamping pins are sleeved in clamping pin springs and then arranged in two locating holes of a fishing line wheel main body. One ends, protruding out of the locating holes, of the clamping pins are spherical bodies. The release hole is disposed at a position, corresponding to the clamping pins, of the lever handle. The release hole is a through hole and provided with a step in the hole which divides the release hole into a big hole area and a small hole area. The big hole area is located at one end, towards to the clamping pins, of the release hole. The outer edge of the big hole area is provided with two inclined planes which are used for pressing the clamping pins into the locating holes. The release button is arranged in the small hole area. Through adjustment of the positions of the clamping pins, when the brake lever locating mechanism of the fishing line wheel is used, damages to the appearance can not occur, and the service life of products is prolonged.