The utility model discloses a splicing dislocation mechanism of a box pasting two-piece splicing device, wherein a dislocation air cylinder and a dislocation clapper are mounted on a side face of a lower shifting board; one end of the dislocation air cylinder is connected with the lower shifting board; the other end of the dislocation air cylinder is connected with the dislocation clapper; the dislocation clapper moves along the slant direction through air supply of the dislocation air cylinder; an abutting block is mounted on the lower shifting board; an air cylinder is mounted below the abutting block; the abutting block is connected with the air cylinder mounted below the abutting block; the air cylinder mounted below the abutting block is fixed on the lower shifting board; the abutting block moves upward through the air cylinder; a first paper pushing air cylinder and a second paper pushing air cylinder are locked on an air cylinder support block of a number one lower shifting board; a paper pushing board is connected with the first paper pushing air cylinder and the second paper pushing air cylinder; and the paper pushing board moves forward through air supply of the first paper pushing air cylinder and the second paper pushing air cylinder. The splicing dislocation mechanism achieves automatic splicing dislocation of two-piece splicing, not only improves accuracy, but also improves efficiency.