The utility model relates to a setting tool penetrating a cable packer. The setting tool penetrating the cable packer is characterized by comprising an upper end sealed chamber, a ball seat, a ball seat upper protection cover and an outer sleeve. The upper end sealed chamber is connected with the outer sleeve in a threaded mode, and the connection position between the upper end seal chamber and the outer sleeve is sealed by a sealing ring. The ball seat is installed in the upper end sealed chamber, the ball seat and the upper end sealed chamber are fixed through shear pins, and steel balls are arranged in the ball seat. The setting tool of the cable penetrating packer has the advantages that a landing nipple does not need to be released into the downhole when a set penetrates the cable packer, the operation process that a plug is thrown into by a steel wire can be saved, and compared with the structure of a check valve, the setting tool penetrating the cable packer can enlarge an effective orifice area of oil extraction. When remedial work is carried out, convenience is brought to well washing. The setting tool penetrating the cable packer is reasonable in structure design, convenient to operate and use and capable of substantially reducing work cost.