The utility model discloses a full-automatic cleaning defogging device for a spectacle, and is used for solving the problems of cleaning and defogging of the spectacle. A motor, a water pump and a hot air blower are connected in parallel with a controller; a rotating rod is arranged on a rotating shaft of the motor; a spectacle support is fixed on the rotating rod; a water inlet tube and a water outlet tube are connected with the water pump; a spray nozzle is connected with the water outlet end of the water outlet tube; a hot air head is arranged at an air outlet of the hot air blower; and the blower, the water pump, the hot air blower and the controller are connected with a power supply. The full-automatic cleaning defogging device can clean and defog the spectacle, so that the sanitation of the spectacle is effectively improved.