The utility model relates to a two-machine or multi-machine and one-tower desulfurization device applicable to a sintering system. The two-machine or multi-machine and one-tower desulfurization device comprises a flue gas system, a sulfur dioxide absorption system, a limestone slurry preparation system, a process water system, a gypsum dehydration system and a desulfurization draindown system which are matched to complete the absorption on the sulfur dioxide. The desulfurization device has the advantages of being low in cost and high in efficiency; and a tangential nozzle and an FRP (Fiber Reinforced Plastics) spraying pipeline which are prepared by silicon carbide are corrosion-resistant, and capable of preventing gypsum scaling and blocking.