The utility model discloses a multi-function portable operation folder. The problems that used tools are complex and easy to leave out in the switching operation process of transformer substation operation personnel are solved. The multi-function portable operation folder comprises a folder cover page (2) and a folder back cover page (1), a rain-proof transparent page (3) is arranged between the folder cover page (2) and the folder back cover page (1), a calculator, a five-prevention key (8) and an article bag (10) are respectively arranged on the back face of the folder cover page (2), and a ticket folder (5), a pen bag (7) and a recording pen (6) are respectively arranged on the inner side face of the folder back cover page (1). The multi-function portable operation folder is compact in structure, various conditions encountered in the actual switching operation process are fully utilized and considered, and the switching operation work of the operation personnel is conveniently carried out.