Provided is a folding arm type high-voltage isolation switch. The folding arm type high-voltage isolation switch comprises a static contact, a driving mechanism including a transmission seat and a motor, and a moving contact assembling body, wherein the moving contact assembling body comprises a moving contact, a lower conductive pipe and an upper conductive pipe; the lower conductive pipe and the upper conductive pipe are rotationally connected; a first slider-crank mechanism arranged in the lower conductive pipe comprises a draw plate and a pull bar; the draw plate is provided with a tooth bar; the tooth bar is engaged with a gear; the gear is fixedly connected with the upper conductive pipe through a first connecting shaft; the slider-crank mechanism arranged between the driving mechanism and the lower conductive pipe comprises a connecting lever and a hexagonal screw; the upper conductive pipe is connected with a moving contact seat; a clamping mechanism is disposed on the moving contact seat; and the output end of the clamping mechanism is provided with a moving contact bar. The folding arm type high-voltage isolation switch is characterized in that a second slider-crank mechanism arranged between the lower conductive pipe and the clamping mechanism comprises a first connecting plate, a second connecting plate and a sliding bar, and through the reciprocating motion of the sliding bar, the moving contact of the clamping mechanism is clamped and loosened relative to a static contact pipe.