The utility model discloses a submerged arc furnace lining with a vertically laid large carbon brick. The submerged arc furnace lining comprises a furnace bottom and a hearth; a phosphatic fireproof concrete layer and a high aluminum brick layer are successively arranged at the furnace bottom from top to bottom; a carbon ramming material layer or a low temperature thick seam pasting layer is arranged on the high aluminum brick layer; the vertically laid large carbon brick is arranged on the inner wall of the hearth; and the height of the vertically laid large carbon brick is 692 mm or 1200 mm. According to the utility model, multiple layers of small annular carbon bricks in a hearth in the prior art are replaced by the vertically laid large carbon brick, so brick work joints are greatly decreased, air-tightness and overall intensity of the hearth of a submerged arc furnace are improved, and smelting intensity of a reaction zone is effectively increased. A firm slag iron housing protective layer can be formed away from electrodes in a weld crater to effectively protect the furnace wall, so the carbon brick is adequately protected from erosion by high temperature gas, mechanical and chemical erosion resistant ability are enhanced, and service lifetime of the submerged arc furnace lining can be effectively prolonged.