The utility model belongs to the technical field of centrifugal compressors, particularly relates to a centrifugal compressor diffuser blade structure, wherein a plurality of diffuser blades are uniformly distributed on a blade plate along the peripheral direction, and are of an arc shape, and cone-shaped structures are arranged on the front edges of the diffuser blades. The front ends of the diffuser blades comprise top sides, pressure surface sides and suction surface sides, and the top sides, the pressure surface sides and the suction surface sides are chamfered to form the cone-shaped structures. The centrifugal compressor diffuser blade structure is applied in a big centrifugal air compressor unit, can effectively reduce total vibration of pipelines, in particular to vibration amplitude of the blades under frequency, and prevents shut-down accidents of centrifugal compressors caused by damage of pipelines from happening.