The utility model relates to a winding transposition structure of a large transformer and belongs to the technical field of large transformer manufacturing. The technical scheme adopted by the utility model is as follows: a horn-shaped cushion block (2) is arranged between two adjacent wire discs of a winding (1), and the position of the horn-shaped cushion block (2) is matched with the inner radius and outer radius of the winding (1); one side of the horn-shaped cushion block (2) is tightly adhered to the adjacent arc surfaces of the wire discs, and the other side of the horn-shaped cushion block (2) is flush with the inner diameters or outer diameters of the wire discs; the horn-shaped cushion block (2) is made of laminated paper sheets and is horn-shaped; the heights and widths of two ends of the horn-shaped cushion block (2) are matched with the thickness and width of wires of the winding; the length of the horn-shaped cushion block (2) is matched with the inner radius and outer radius of the winding. The winding transposition structure has the beneficial effects of preventing the wire discs of the winding from being subjected to a loosening phenomenon during vacuum drying and oil impregnation processes, therefore effectively enhancing the radial consolidation degree of the wire discs, improving the mechanical strength and short circuit resistance of the winding and ensuring the safe operation of the transformer.