The utility model discloses an intelligent medicine administration device. A box body comprises an outer ring, an inner ring, a rotating rack, at least one medicine box, a motor, a transmission device, a control system, a limiting switch and a medicine taking door; after being divided equally, the rotating rack is arranged between the outer ring and the inner ring; the medicine boxes are placed in a frame of the rotating rack after the rotating rack is divided equally; the control system and the motor are arranged in the inner ring; the motor is connected with the control system; the control system is used for reminding a patient of taking medicines when preset medicine taking time is up; the motor is started to drive the transmission device so as to drive the rotating rack to rotate; the limiting switch is fixed on the inner wall of the inner ring, so that the rotating rack stops when rotating around the frame once at a time; and the medicine taking door is arranged on the outer wall of the outer ring. Only one medicine box can be opened at a time on medicine taking time; after medicine administration time is over, medicines cannot be taken; reliability and safety on medications are improved; total medicine administration frequency of medicine adding at a time can be set; and the intelligent medicine administration device is particularly suitable for patients who take medicines repeatedly for a long time.