The utility model provides a hollow block with end side plates and middle separator all formed with connecting notches. The hollow block comprises at least front and rear side plates, left and right end side plates and the middle separator, wherein the middle separator is used for equally dividing the internal cavity of the block into left and right parts; first connecting notches are formed in the upper and lower end faces of the left and right end side plates in corresponding positions, respectively; the first connecting notches penetrate through the cavity; second connecting notches are formed in the upper and lower end faces of the middle separator in corresponding positions, respectively, and the left and right cavities are communicated by use of the second connecting notches. When the hollow block with the end side plates and the middle separator all formed with the connecting notches is applied to building a wall, a plurality of such hollow blocks are connected by use of special connecting pieces so that the adjacent blocks can be fixedly connected together; the brickwork or the wall built with the blocks is connected integrally and directly after being built and no adhesive mortar is applied between the adjacent blocks; while building, the pouring of a core column can be carried out immediately after reinforcing so that the construction speed of the reinforced brickwork can be increased.