The utility model discloses a continuous inactivation treatment device for biological wastewater. The continuous inactivation treatment device for the biological wastewater comprises a liquid storage tank, a circulating pump, a heating device, a heat preservation device, a thermal energy recovery device and a cooling device, wherein the first output end of the liquid storage tank is connected with the circulating pump; the second output end of the liquid storage tank is connected to a biological waste material discharge device through a first regulating valve; the output end of the circulating pump is connected with the heating device; the output end of the heating device is connected with the heat preservation device; the output end of the heat preservation device is connected with the thermal energy recovery device; the output end of the thermal energy recovery is connected with the cooling device; the output end of the cooling device is connected to the biological waste material discharge device through a second regulating valve. The continuous inactivation treatment device for the biological wastewater, provided by the utility model, is high in safety and stability; the continuous inactivation treatment device for the biological wastewater has the advantages of low energy consumption and good inactivation effect. Therefore, the using requirements for the biological pharmaceutical enterprises and bio safety laboratories can be met.