The utility model relates to a valve wrench, and particularly relates to an anti-slip adjustable operation handle valve wrench. The anti-slip adjustable operation handle valve wrench comprises an operation handle; the front end of the operation handle is connected with a claw disc; two and more than two right-angle claws are arranged on the claw disc; the right-angle claw is a vertical claw; the outer end of the vertical claw is connected with a transverse claw forming a 90 DEG angle with the vertical claw to play the anti-slip role; the operation handle can be made into a telescopic rod structure, the length of a level is increased, the inner rod is screwed into the inner end of the outer sleeve rod in the unused case, the length is reduced, and placement is facilitated. When the wrench of the utility model is used for pulling the valve, the slip phenomenon does not happen as the right-angle claws are adopted. As the operation handle is made into the telescopic rod structure, the arm force can be increased without carrying a casing, the inner rod can be down out when a person can not operate conveniently or the distance is too long, and the labor-saving operation effects can be achieved.