The utility model discloses a gas welding and cutting operation combination wrench, which is used for assisting to complete daily operation of assembling and disassembling of a gas meter, assembling and disassembling of a cutting gun, opening and closing of a gas cylinder, replacing of a cutting torch and the like during manual gas welding and gas cutting operation. The combination wrench comprises a body, wherein the body is provided with a cutting gun nozzle wrench part, an acetylene cylinder wrench part, an oxygen meter wrench part, a gas passage connector wrench part and an oxygen cylinder wrench part, the cutting gun nozzle wrench part and the acetylene cylinder wrench part are in inward square shapes and are arranged at one end of the body, and the oxygen meter wrench part, the gas passage connector wrench part and the oxygen cylinder wrench part are opened and are arranged at the other end of the body. According to the gas welding and cutting operation combination wrench disclosed by the utility model, multiple dedicated wrench parts are arranged on one wrench, the operation is convenient, the working efficiency of construction preparation and completing of gas cutting and gas welding operation and construction are effectively increased, and the effective work operation time is increased; the size is small, the weight is light, the combination wrench is not limited by narrow space during an operating process, the space is not occupied when the combination wrench is put in a tool box, the carrying is convenient, and the maintenance is easy.