Disclosed is a hydraulic setting multi-layer simultaneous extraction pipe column. The hydraulic setting multi-layer simultaneous extraction pipe column overcomes the defects that during deep well development of an existing multi-layer simultaneous extraction pipe column, due to the fact that compressive loads of an oil-well pump are large, eccentric wear of a rod, a pipe and a plunger is serious, and a pumping rod is broken off. An oil-well pump of the hydraulic setting multi-layer simultaneous extraction pipe column is an overbridge selective extraction pump. A packer is a hydraulic packer. The lower end of an oil pipe is sequentially and fixedly connected with the overbridge selective extraction pump, the hydraulic packer and an anti-blocking valve. The oil pipe is installed between the hydraulic packer and the anti-blocking valve. The anti-blocking valve is located on a lower oil layer. The overbridge selective extraction pump is located on an upper oil layer. The hydraulic setting multi-layer simultaneous extraction pipe column has the advantages that the structure is simple, and the design is reasonable; in the crude oil lifting process, the phenomenon that a pumping rod, the oil pipe and a plunger are eccentrically worn can be effectively avoided, the non-production working time of replacement and maintenance is greatly shortened, the productive efficiency is improved, and the hydraulic setting multi-layer simultaneous extraction pipe column is particularly applicable to deep-well crude oil extraction.