The utility model relates to an oil-water well inserting type downhole operation safety joint capable of being used in cooperation with a rotary setting packer. Forward rotation setting of the packer and reverse rotation reversing of a downhole pipe column can be met at the same time, and releasing operation of the downhole pipe column is facilitated. The oil-water well inserting type downhole operation safety joint comprises an upper joint body and a lower joint body, and a loading limit protection mechanism is arranged between the upper joint body and the lower joint body. The loading limit protection mechanism is provided with a shear pin, a blocking cap and a connecting sleeve, the blocking cap is in threaded connection with the connecting sleeve, the upper joint body is connected with the blocking cap through the shear pin, and the lower joint body is in threaded connection with the connecting sleeve. The blocking cap and the upper joint body are connected through the shear pin, and can be sheared off under the designed lifting additional load. The oil-water well inserting type downhole operation safety joint is safe and reliable, normal production can be guaranteed, forward rotating setting of the rotary setting packer is met, when the packer is clamped and blocked, the pipe column on the upper portion of the safety joint can be tripped out safely, and construction of the downhole operation pipe column is greatly facilitated.