The utility model discloses a skid-mounted purification system which comprises a bearing base, wherein a gas source inlet, a purified gas outlet and a venting outlet are formed in the edge of the bearing base; a deacidification skid, a dehydration skid and an underground storage tank skid which are detachable are arranged on the bearing base; the gas source inlet is sequentially communicated with a filter separator, a feed gas exchanger and the lower part of an absorption tower respectively, the filter separator, the feed gas exchanger and the absorption tower are arranged on the deacidification skid, the bottom of the absorption tower is communicated with a regeneration system arranged on the deacidification skid and then enters the underground storage tank skid, gas generated in the regeneration system is exhausted to the outside through the venting outlet, the top of the absorption tower is communicated with a separation filtering system arranged on the deacidification skid and then enters the dehydration skid, and gas after the dehydration treatment by the dehydration skid is exhausted to the outside. According to the skid-mounted purification system, space of skid bodies is used effectively through reasonable layout, and structural integration and functional centralization for purification system equipment in a liquefied natural gas device are achieved, so that the occupied area is reduced.