The utility model provides a dust-proof pressure measuring device of high-pressure gases. The device comprises a sensor, an air inlet front end of the sensor is provided with thousand-mesh steel wire gauze, the thousand-mesh steel wire gauge is fixed on the air inlet front end of the sensor through a fixing member, high-pressure gases containing dust is filtered by the thousand-mesh steel wire gauze into clean gases, and gas pressure is converted into electrical signals by the sensor after entrance of the gases. With adoption of the dust-proof pressure measuring device, high-pressure gases containing dust can be effectively prevented from blocking a measuring duct or a pressure guiding tube, so as to ensure normal measurement of gas pressure, and avoid potential safety hazards. An anti-blocking device adopted by the measuring device is simple in structure, low in cost and excellent in dust filtering effect.