The utility model discloses an eccentric shaft seal structure with a bushing. A first mounting hole is formed in the center of a casing, and a circular second mounting hole is formed in the periphery of the first mounting hole to be used for mounting a framework oil seal. An eccentric shaft penetrates the first mounting hole of the casing, and one end of the eccentric shaft is connected onto the casing by the supporting of bearings and extends towards the outside of the casing to be in contact with a framework oil seal lip. A bushing is sleeved on the contact position of the eccentric shaft and the framework oil seal and is disposed between the eccentric shaft and the framework oil seal. According to the structure, the eccentric shaft with the bushing is formed by the bushing and the eccentric shaft, the bushing size is small, the structure is simple, the rigidity is easy to guarantee through heat treatment, the surface coarseness can be guaranteed easily through grinding, and accordingly, the service lives of the bushing and the framework oil seal are increased, the oil leakage rate is reduced, and only the bushing is needed to be changed if the bushing on the eccentric shaft seal structure is damaged, the eccentric shaft is not needed to be changed, and accordingly, the cost is reduced.