The utility model discloses a with filling is compound from insulation block, including two main lobe pieces that set up with the symmetry of volume, at the through-hole that link up main lobe piece both ends that the both sides of main lobe piece were equipped with respectively that a length direction along the main lobe piece sets up, be equipped with between two main lobe pieces along main lobe piece length direction and extend the heat preservation that sets up, two main lobe pieces and heat preservation an organic whole are made. The above technical scheme is adopted in the utility model, structural design is equitable, and the centre with filling is equipped with the heat preservation, and the pressure-bearing is even, build that the wall body is stable not to come off by laying bricks or stones, the whole disconnections of cold and hot bridge, and it is effectual to keep warm, adopts two main lobe pieces, does not have the siphonal lobe piece, does not have inside and outside branch, construction convenience when building the wall body by laying bricks or stones, has just improved the bearing strength of building block self greatly, and 15Mpa can be accomplished to the maximum intensity.