The utility model provides a multi -functional dustproof computer machine case solves dust that traditional main frame machine case exists and is difficult to to handle and causes quick -witted incasement to be difficult to reach ideal operating temperature's problem easily, and its technical scheme is: including the box, be equipped with the installation position that is used for installing electronic components on the medial surface of box, the box of saying be upper end and lower extreme open -ended cavity structures, and the other sealing connection of the upper and lower port punishment of box has the semiconductor refrigeration piece, and the cold junction of two semiconductor refrigeration pieces is inside the box, and the contact of the hot arc hot junction of semiconductor refrigeration piece is connected with the conducting strip, and the outside cover of conducting strip is equipped with and is used for dirt -proof cover to personally experience sth. Part of the body, covers to be equipped with a plurality of ventilation holes, the semiconductor refrigeration piece electric connection power supply who says on personally experiencing sth. Part of the body. The utility model discloses the dust that isolated external environment had stopped in the outside air gets into quick -witted incasement, adopt simultaneously the semiconductor refrigeration piece in to the box temperature adjust.