The utility model provides a large -scale waters quality of water control sampling integration system based on unmanned aerial vehicle, including unmanned aerial vehicle, ground measurement and control center and hand held mobile terminal, unmanned aerial vehicle carries there is the unit of taking a picture in the air, aerial camera unit, the flight control unit, the water quality monitoring unit, aerial measurement and control center and water sample acquisition unit, the unit of shooing in the air, aerial camera unit, the flight control unit, water quality monitoring unit and water sample acquisition unit link to each other with aerial measurement and control center, aerial measurement and control center and the communication connection of ground measurement and control center, ground measurement and control center and hand held mobile terminal communication are connected. The utility model discloses synthesize means such as the application is taken photo by plane, water quality automatic monitoring, the quality of water situation and the pollutant emission situation of the important waters of the control target department of cruising to on -the -spotly as required gathering and preserveing the water sample, give the hand held mobile terminal with information propelling movements such as quality of water situation and water pollution situations fast, for the daily quality of water control sample in large -scale waters, and the proruption water pollution is emergent, and respond and the management provides decision support the platform.