The utility model discloses a multi -functional dustproof computer machine case, including box, side boxboard, preceding boxboard and back boxboard, be equipped with the start control switch on the preceding boxboard, be equipped with the protection viewing aperture on the side boxboard, the protection viewing aperture demountable installation of department has the guard plate, the bleeder vent has been seted up on the guard plate, be equipped with the air intake on the side boxboard, orientation in the box air intake department is equipped with the air inlet fan, be equipped with the air exit on the back boxboard, orientation in the box air exit department is equipped with the fan of airing exhaust, top and lateral part in the box are equipped with the filter screen respectively, preceding boxboard with install the dust catcher on the side boxboard respectively, the dust catcher is connected with dust removal control switch. The utility model discloses simple, the convenient to use of structural design, the reliability is high, in the box dust do not have overstocked, dust removal effect good, does benefit to extension equipment life.