The utility model discloses a litchi cross breeding isolative protection screen panel, it includes: the screen panel skeleton, it covers on litchi tree's tree crown, coverage network, its with the mode housing that can dismantle in on the screen panel skeleton, and its lower extreme buries soil and is fixed in ground, this coverage network quilt the screen panel skeleton struts to it is used for the independent space that separates selected litchi tree and other fruit trees to form one, a business turn over door has been seted up to this coverage network's side, and the top cover plate, its mode lid in order dismantling is located coverage network's top to play the effect of taking shelter from rain. The utility model discloses a coverage network and top cover plate cover that whole litchi tree prevent wind in order to keep apart different trunk pollen and pollination entomophila, can also play simultaneously, the effect of rain -proof, the insect pest of preventing disease to show improvement litchi cross breeding work efficiency and hybridization success rate. The utility model has the advantages of simple structure, the convenience that just removes with low costs, practical, it can also used repeatedly to use manpower sparingly, material resources and financial resources.