The utility model discloses a precision positioning adjusting device includes: remove and carry on the frame, the walking ware, the L support that appears, the carrier, rotation axis and location base, the guide rail is equipped with on moving the lift -launch frame, the walking ware is equipped with on the guide rail, be fixed with L shape support on the walking ware, the base of L shape support is fixed at the walking ware, the side of L shape support is fixed with the carrier, the orientating group seat is equipped with on the carrier, the rotation axis is equipped with on the carrier, the one end of rotation axis links to each other with the one end of reduction gear, the other end of reduction gear is equipped with the knob, fixed cover is equipped with the one end of an at least connecting rod on the rotation axis, the other end of connecting rod is fixed on the base of location, it makes the rotation axis carry out the trace rotation to rotate the knob, and then make the location base carry out the trace swing round the rotation axis, with the precision positioning who realizes the location base, the utility model discloses a precision positioning adjusting device has promoted greatly and has markd the positioning accuracy of subassembly, and can make things convenient for, swiftly carry on the image demarcation, has promoted experimental efficiency.