The utility model discloses a gel electrophoresis and observation all -in -one, including outer protective shell and monitoring device, outer protective shell's inside is equipped with monitoring device, electrophoresis tank and base power, monitoring device comprises metal support bar and camera, the camera passes through screw rod and metal support bar's top end screw thread connection, metal support bar's the bottom and the cell wall threaded connection of electrophoresis tank bottom, the top threaded connection of screw rod and base power is passed through to the bottom of electrophoresis tank, the inslot of electrophoresis tank is equipped with the light filter, the bottom of light filter is equipped with six roots of sensation ultraviolet fluorescent tube, the inside of base power is equipped with constant voltage power supply. The utility model discloses make experiment sample application, electrophoresis all accomplish in the electrophoresis tank to last observation result's whole experimentation, effectively avoided original experiment operation in fairly large experiment pollute, in the experiment process, can carry out in situ observation and control to experiment phenomena's change through transparent electrophoresis tank, can improve experimental efficiency effectively and test the quality of instruction.