The utility model relates to an insulating seal device that pipeline station field and valve chamber flange formula instrumentation connect. Instrumentation's flange A passes through the insulating pad connection of flange with the connection face of getting the flange B of source block, and flange A and flange B's link passes through bolted connection: insulation support passes flange A and flange B's flange hole in proper order, inside metal fastening bolt passes insulation support, just be equipped with metal nut, metal spring packing ring and insulating nut collar between metal fastening bolt's both ends and flange A's upper surface and flange B's the lower surface respectively in proper order. The utility model discloses can eliminate electrochemical corrosion, improvement pipelines in operation's fail safe nature, make the pipe -line construction more tend to standardization, modularization, hommization, reduction construction process and material, make things convenient for the operation maintenance, reduce equipment investment and operating expenses.