The utility model discloses an operating room is with preventing infecting liquid waste collection device, including first collection box, first aspirator pump, first pipeline, the suction nozzle, the memory iron wire, first solenoid valve, the second solenoid valve, velocity of flow sensor, the filter screen, the box is collected to the second, the second aspirator pump, the second pipeline, this operating room is with preventing infecting liquid waste collection device, the structure is ingenious, powerful, easy operation, through using the device, it removes and removes to make the suction nozzle can follow the mirror sheath, avoid the waste liquid outflow the device outside of collecting and cause the infection to sterilized dressing, play effectual guard action to sterilized dressing, simultaneously, the device can separate the collection with waste liquid and rubble, and the device is also advantaged by ingenious structure, functions are powerful,