The utility model discloses a novel large -scale factory building dust pelletizing system has solved among the prior art tall and big space factory building and has detached the dust inefficiency, problem that removal amount is few. The utility model discloses a top exhaust units install at the top of factory building and switch on mutually with the outside air, girder steel guide rail symmetry isinstalled in the inside of factory building, integration purification fan group removes the frame through the fan and connects on the girder steel guide rail, integration purification fan histotope in top exhaust units's below, integration purification fan group includes a plurality of axial fan and a plurality of and the corresponding dust collector of axial fan, and dust collector installs on axial fan's upper portion, and axial fan's lower part is equipped with the dust concentration sensor that is used for perception dust concentration. The utility model relates to an it is ingenious, canrealize all -round dust removal, the dust collection efficiency is high, both can go circulation indoor and outdoor air, can realize indoor air circulation alone again, improves the interior operational environment of factory building greatly, and is energy -concerving and environment -protective.