The utility model discloses a hemodialysis pipe is with fixing device who has locate function, including bandage, solid fixed ring, swivel becket, knock pin, the hole of stepping down, sponge, leakageliquid sensor, alarm, this hemodialysis pipe is with fixing device who has locate function, the structure is ingenious, powerful, easy operation through using the device, can advance that line location is fixed to be handled to the pipe, effectually prevents pipe from the internal emergence that the phenomenon appears breaking away from of patient, plays the guard action to the patient, has guaranteed patient's therapeutical progress.