The utility model relates to the technical field of automobile high-voltage wiring harnesses, in particular to a new energy high-voltage wiring harness. The wire harness includes: a wire harness body;the utility model discloses a cable, an electromagnetic shielding protection joint and an anti-cut protection device. The cable includes: a cable body; wherein the plurality of new energy high-voltage wire cores, the high-temperature-resistant ethylene propylene rubber layer, the graphite layer, the carbon fiber composite strong nylon woven reinforcing layer, the copper foil layer, the polytetrafluoroethylene plastic insulating layer, the conductive cloth layer, the wear-resistant outer sheath layer and the nano zinc oxide coating layer are arranged inside the cable; the nano zinc oxide coating layer is coated outside the wear-resistant outer sheath layer; the anti-cutting protection device is installed at the threading position of a metal plate, and the electromagnetic shielding protection connector is installed at the end of a cable. The graphite layer is used as the electromagnetic shielding layer, compared with a metal film, the electromagnetic shielding layer has the advantages of being better in conductivity and higher in bending resistance, the electromagnetic shielding effect is better, and the end of the new energy high-voltage wire harness can also have the anti-interference capacity through the shielding cylinder arranged on the connector.